What is the average CRNA pay in South Carolina?

The average advertised W-2 base salary is $232,857 in South Carolina. That figure comes from BagMask’s Q2 2026 CRNA Salary Report; individual offers vary by experience, schedule, employer, and tax status.

What license does a CRNA need in South Carolina?

South Carolina CRNAs need current RN authority and South Carolina APRN licensure in the CRNA specialty. The South Carolina Board of Nursing requires qualifying graduate education, current specialty certification, required verifications, and an APRN application before advanced nursing practice begins.

Which South Carolina areas are hiring the most CRNAs?

Columbia, Myrtle Beach, and Florence currently have the largest concentrations of active BagMask listings. This answer updates with the live inventory, so the leading markets may change as jobs are added or closed.

South Carolina CRNA directory

CRNA Jobs in South Carolina

South Carolina CRNA pay varies by employer, experience, schedule, and tax status. BagMask Q2 2026 CRNA Salary Report reports a average advertised W-2 base salary of $232,857 in South Carolina. The live BagMask listings below stay synchronized with active openings; open a job to review employer-provided compensation, schedule, time off, and benefits when available.

South Carolina uses two personal state income tax brackets for 2026. Candidates comparing offers should also weigh housing, commuting, insurance, and any expenses that come with a 1099 arrangement.

For national compensation context, read BagMask’s highest-paying W-2 CRNA jobs, then compare each South Carolina opening by location, schedule, time off, and employer.

Current BagMask listings: 97
South Carolina advertised average: $232,857
Personal state income tax: 1.99% or 5.21%

Search all South Carolina CRNA jobs

All current CRNA jobs in South Carolina

Published October 5, 2026

Current CRNA jobs in South Carolina
Location	Position	Employer	Job
Charlotte, SC	Charlotte Suburb to $400K & a Happy Workplace for CRNA’s + Bonus & Flex Shifts	GoldMatch Healthcare Solutions	View job
SC	Northern SC CRNA – Salaries to the $300KS plus OT and 8,10, or 12 hr Shifts	GoldMatch Healthcare Solutions	View job
Family friendly, SC	SC CRNA – High-Pay and OT Potential – Salaries Increase Quickly	GoldMatch Healthcare Solutions	View job
Fort Mill, SC	Expanding private practice in the south Charlotte suburb area. Variety of shifts across 2 locations available.	Anesthesia Associates of Rock Hill	View job
Columbia, SC	Central SC CRNA \| 1099 $370K+ \| 13 Weeks Off \| 45 Min to Columbia	CompHealth	View job
Columbia, SC	CRNA opportunity at Prisma Health Endo Center in one of South Carolina's fastest growing areas. hands-on ACLS/BLS training is required	CRH Anesthesia	View job
Florence, SC	CRNAs Needed in Central SC	Radar Healthcare Providers	View job
SC	Locums Choice seeks a CRNA for coverage in South Carolina.	Locums Choice	View job
Columbia, SC	Central SC \| Outpatient Eye Center \| No Call, Weekends or Holidays \| Excellent Work-Life Balance	CompHealth	View job
SC	CRNA Coverage in Central SC \| 4 or 5-Day Workweek	Medicus Healthcare Solutions	View job
SC	CRNA Locum Tenens Opportunity in Northeastern SC	Medicus Healthcare Solutions	View job
Florence, SC	General \| CRNA	United Anesthesia	View job
SC	Locum Tenens CRNA Opening in Eastern SC	Medicus Healthcare Solutions	View job
SC	Locum Tenens CRNA Opportunity in Northern SC	Medicus Healthcare Solutions	View job
SC	Pediatric CRNA Locum Tenens Opportunity in Charleston, SC	Medicus Healthcare Solutions	View job
Florence, SC	CRNA CRNA - Florence, SC	D&Y Staffing	View job
Camden, SC	Lead CRNA \| MUSC Health is seeking an Exceptionally Organized CRNA Leader \| MUSC Health Kershaw Medical Center, Camden, SC	Medical University of South Carolina	View job
Columbia, SC	🩺 Cardiac CRNA Opportunity (1099) – MUSC Health Columbia Medical Center	Medical University of South Carolina	View job
Florence, SC	Cardiac CRNA (PRN) – 65 miles from SC Beaches- MUSC Health Florence Medical Center	Medical University of South Carolina	View job
Columbia, SC	Cardiac CRNA (PRN) – Very Competitive Compensation- MUSC Health Columbia Medical Center	Medical University of South Carolina	View job
Columbia, SC	Cardiac CRNA \| $50K Commencement Bonus - MUSC Health Columbia Medical Centers	Medical University of South Carolina	View job
Florence, SC	Cardiac CRNA \| $50K Commencement Bonus and 5K Site Incentive \| 65 miles from Beach - MUSC Health Florence Medical Center	Medical University of South Carolina	View job
Columbia, SC	CRNA - $50.000 Commencement Bonus- MUSC Health Columbia Medical Centers	Medical University of South Carolina	View job
Florence, Black River and Marion, SC	CRNA – $50K Commencement Bonus and 5K Site Incentive- MUSC Health Pee Dee Division (Florence, Black River, and Marion, SC)	Medical University of South Carolina	View job
SC	CRNA (1099) \| Very Competitive Compensation! \| MUSC Health Columbia Medical Centers	Medical University of South Carolina	View job
SC	CRNA (1099) \| Very Competitive Compensation! \| MUSC Health Kershaw Medical Center	Medical University of South Carolina	View job
SC	CRNA (Part -Time) - Very Competitive Compensation- MUSC Health Pee Dee Division (Florence, Black River, and Marion SC)	Medical University of South Carolina	View job
Cades, SC	CRNA (PRN) - Very Competitive Compensation- MUSC Health Black River Medical Center- Pee Dee Division	Medical University of South Carolina	View job
Mullins, SC	CRNA (PRN) - Very Competitive Compensation- MUSC Health Marion Medical Center- Pee Dee Division	Medical University of South Carolina	View job
Orangeburg, SC	CRNA (PRN) – Very Competitive Compensation- MUSC Health Orangeburg Medical Center	Medical University of South Carolina	View job
Florence, SC	CRNA (PRN) Very Competitive Compensation – MUSC Health Florence Medical Center- Pee Dee Division	Medical University of South Carolina	View job
Camden, SC	CRNA (PRN) Very Competitive Compensation- MUSC Health Kershaw Medical Center	Medical University of South Carolina	View job
Lancaster, SC	CRNA (PRN)- Very Competitive Compensation near Charlotte, NC - MUSC Health Lancaster Medical Center	Medical University of South Carolina	View job
Columbia, SC	CRNA (PRN)- Very Competitive Compensation- MUSC Health Columbia Medical Centers	Medical University of South Carolina	View job
Florence, SC	CRNA \| General Anesthesia: 24 Hour Shifts, 8 Shifts per month \| MUSC Florence, SC \| $50k Commencement Bonus!	Medical University of South Carolina	View job
SC	CRNA \| No Beeper \| No Call \| No Holidays \| $50K Commencement Bonus, Lancaster SC \| 20 mi from Rock Hill, SC/Waxhaw, NC, 45 mi from Charlotte, NC	Medical University of South Carolina	View job
Camden, SC	CRNA- $50K Commencement Bonus and 5K Site Incentive- MUSC Health Kershaw Medical Center	Medical University of South Carolina	View job
Orangeburg, SC	CRNA: General and OB – $50K Commencement Bonus and 5K Site Incentive - MUSC Health Orangeburg Medical Center	Medical University of South Carolina	View job
Florence, SC	CRNA: MONDAY - FRIDAY 7A - 5P \| No Nights- No Call - No Weekends- $50K Commencement Bonus and 5K Site Incentive \| MUSC Health Florence Medical Center	Medical University of South Carolina	View job
Lancaster, SC	CRNAs \| Join a Collaborative ACT Model \| MUSC Health Lancaster Medical Center, SC	Medical University of South Carolina	View job
Chester, SC	Full-Time Independent CRNA Position \| MUSC Health \| Chester SC \| No Call \| No Weekend \| No Holidays \| $50K Commencement Bonus	Medical University of South Carolina	View job
Columbia, SC	CRNA’s for Central South Carolina - 8s - 24s + $50K Sign-on!	CompHealth	View job
Charleston, SC	Locum CRNA needed in South Carolina.	Odyssey Staffing	View job
Forest Acres, SC	Locum CRNA needed to start ASAP and work ongoing near Forest Acres, SC.	Odyssey Staffing	View job
Forest Acres, SC	Locum CRNA needed to start ASAP and work ongoing near Forest Acres, SC.	Odyssey Staffing	View job
South Greenville, SC	Locum CRNAs needed to start ASAP (30 to 60 days) and work ongoing near South Greenville, SC.	Odyssey Staffing	View job
Woodland Village, SC	Locum CRNAs needed to start ASAP and work ongoing near Woodland Village, SC.	Odyssey Staffing	View job
Charleston, SC	Looking for flexibility, competitive pay, and the chance to shape your own career path?	Odyssey Staffing	View job
Charleston, SC	Looking for flexibility, competitive pay, and the chance to shape your own career path?	Odyssey Staffing	View job
Florence Area, SC	Brand New FT W2 in Metro SC Town! \| Generous Package!	Radar Healthcare Providers	View job
Cherry Grove Beach, SC	Coastal SC Opening! \| Great Work/Life Balance + Generous Pay & Benefits!	Radar Healthcare Providers	View job
Orangeburg, SC	CRNA s Needed in South Carolina	Radar Healthcare Providers	View job
Coastal South Carolina, SC	CRNAs Needed in Coastal South Carolina - Great Pay and Beautiful Location!	Radar Healthcare Providers	View job
Lancaster, SC	CRNAs Needed in Lancaster	Radar Healthcare Providers	View job
Charleston, SC	CRNAs Needed in South Carolina	Radar Healthcare Providers	View job
East SC \| Near NC Border, SC	Excellent W2 Need at Small SC Hospital! \| Great Pay + Benefits!	Radar Healthcare Providers	View job
Florence Area, SC	FT W-2 Cardiac Need in SC! \| Excellent Salary, Benefits, and Schedule!	Radar Healthcare Providers	View job
Greenville SC area, SC	Greenville, SC - CRNA help - Oct 7 and future dates	Radar Healthcare Providers	View job
Metro Charlotte (SC side), SC	Metro Charlotte (SC) - CRNA - outpatient - Sept 9 and future dates	Radar Healthcare Providers	View job
Myrtle Beach Area, SC	New Perm W2 Need! / 235-245K - SC Coastal Surgery Center - January 25' Start!	Radar Healthcare Providers	View job
Charelston, SC	Perm CRNA opening	Radar Healthcare Providers	View job
Coastal South Carolina, SC	Perm CRNA opening - Great Compensation package!!	Radar Healthcare Providers	View job
Central SC, SC	Permanent W2 CRNA's Needed to Join a Hospital Based System! Competitive Comp and Benefits Package! ASAP Start	Radar Healthcare Providers	View job
Upstate South Carolina, SC	PRN Needs in Upstate SC!	Radar Healthcare Providers	View job
Cheraw Area, SC	Rural SC Hospital Needing FT CRNA! \| Excellent W2 Package + Benefits	Radar Healthcare Providers	View job
Northeastern, SC	Rural SC Hospital! \| ASAP Start - Generous Package & Benefits!	Radar Healthcare Providers	View job
Cherryvale, SC	Locum CRNAs needed to start ASAP and work a 6 month assignment with option to extend at a facility near Cherryvale,.	Odyssey Staffing	View job
Myrtle Beach, SC	Locums CRNA Opportunity in South Carolina.	Odyssey Staffing	View job
SC	CRNA Needed for Locum Coverage at Inpatient Hospital in South Carolina	LocumTenens.com	View job
SC	CRNA Needed for Locum Tenens Coverage at Inpatient Facility in South Carolina	LocumTenens.com	View job
SC	CRNA Needed for Locum Tenens Coverage at Inpatient Facility in South Carolina	LocumTenens.com	View job
SC	CRNA Needed for Locum Tenens Coverage at Inpatient Facility in South Carolina	LocumTenens.com	View job
Cayce, SC	Locum CRNA needed to start ASAP and work 6 months with a possibility of extension at a facility near Cayce, SC.	Odyssey Staffing	View job
Myrtle Beach, SC	Locum CRNA needed in South Carolina.	Odyssey Staffing	View job
Alcolu, SC	24-hr. shifts for CRNAs in South Carolina!	CompHealth	View job
Danwood, SC	Cardiac CRNA needed in South Carolina - $45K Signing Bonus	CompHealth	View job
York, SC	Charlotte area CRNA – 4 Day Work Week for ASC - $25K Sign-On Bonus!	CompHealth	View job
Myrtle Beach, SC	CRNA CRNA - Myrtle Beach, SC	D&Y Staffing	View job
Myrtle Beach, SC	Myrtle Beach, SC - Staff CRNA’s for Outpatient Cases	CompHealth	View job
Myrtle Beach, SC	Oceanfront South Carolina seeks Permanent CRNA’s	CompHealth	View job
Little Rock, SC	SC CRNA - 12, 24-Hour Shifts/Month – W2 w/ Full Benefits	CompHealth	View job
Little Rock, SC	SC CRNA - Near the NC border, Autonomy w/ Option to live in Myrtle Beach	CompHealth	View job
Woodland Park, SC	South Carolina CRNA - 8, 10, 12, 16, or 24s - 1-hr. to Columbia	CompHealth	View job
Woodland Park, SC	South Carolina CRNA - 8, 10, 12, 16, or 24s - 1-hr. to Columbia	CompHealth	View job
Charleston Area, SC	South Carolina CRNA 90-minutes to Columbia/Charleston – 10-hr. shifts + Regionals	CompHealth	View job
Myrtle Beach, SC	Staff CRNA’s near the South Carolina Coast!	CompHealth	View job
Windsor Park, SC	Work Independently and No OB for CRNA’s in a Charming SC Town	CompHealth	View job
SC	Certified Registered Nurse Anesthetist in South Carolina \| 200K plus 10K Sign On	Jackson Physician Search	View job
Myrtle Beach, SC	CRNA in Myrtle Beach, SC at Grand Strand Medical Center	TeamHealth	View job
Myrtle Beach, SC	CRNA in Myrtle Beach, SC at Grand Strand Regional Medical Center	TeamHealth	View job
Myrtle Beach, SC	CRNA in Myrtle Beach, South Carolina at Grand Strand Regional Medical Center	TeamHealth	View job
Greenville, SC	Pediatric Dental CRNA – South Carolina \| $250K-$270K \| Part-Time/Full-Time Available	KTE	View job
Murrells Inlet, SC	Work At The Beach And Enjoy Generous Compensation With Flexible Scheduling Options. Tidelands In Top 150 Hospitals To Work 3 Years In A Row!	Tidelands Health	View job
Columbia, SC	CRNA's needed for prn in South Carolina!	Revolution Healthcare Services	View job
West Columbia, SC	$50k Sign On + Work-Life Balance \| Join Magnet-Recognized Lexington Health (Columbia, SC)	Lexington Medical Center	View job
Charleston, SC	Build your career where coastal living meets clinical excellence. Join Trident Anesthesia Group in Charleston for a collaborative culture, practice autonomy, flexible opportunities, and an exceptional quality of life inside and outside the OR.	Trident Anesthesia Group	View job
SC	South Carolina has a need for a Locum CRNA’s at their hospital starting asap!	Greenstaff Medical	View job

Quick answers

South Carolina CRNA jobs: pay, licensing, and hiring areas

What is the average CRNA pay in South Carolina?: The average advertised W-2 base salary is $232,857 in South Carolina. That figure comes from BagMask’s Q2 2026 CRNA Salary Report; individual offers vary by experience, schedule, employer, and tax status.
What license does a CRNA need in South Carolina?: South Carolina CRNAs need current RN authority and South Carolina APRN licensure in the CRNA specialty. The South Carolina Board of Nursing requires qualifying graduate education, current specialty certification, required verifications, and an APRN application before advanced nursing practice begins.
Which South Carolina areas are hiring the most CRNAs?: Columbia, Myrtle Beach, and Florence currently have the largest concentrations of active BagMask listings. This answer updates with the live inventory, so the leading markets may change as jobs are added or closed.